Réaction #216979

Équation de réaction

triethylphosphite

bromomethyl methyl ether

→

title compound

Rendement 98.0%

(Methoxymethyl)phosphonic acid, diethyl ester

Rendement 98.0%

Conditions de réaction

Traitement

1. 1
   workup.DISTILLATIONwhen it was fractionally distilled (bp 100° C., 5 mm)

Mode opératoire

To a sample of 17.90 mL (0.104 mol) of triethylphosphite at -78° C. under argon was added dropwise 8.50 mL (0.104 mol) of bromomethyl methyl ether. The mixture slowly warmed to RT and stirred for 24 h, when it was fractionally distilled (bp 100° C., 5 mm) to provide 16.22 g (98%) of title compound as a pale yellow oil.

Source