Réaction #2146088

Équation de réaction

N-benzylaniline

4-fluorophenyl phosphonic dichloride

→

1-(4-fluorophenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide

Rendement 30.0%

Conditions de réaction

Traitement

1. 1
   Autreto yield a pale yellow solid
2. 2
   AutreThe yellow solid was recrystallized from ethyl acetate

Mode opératoire

The procedure of Example 26 was employed utilizing N-benzylaniline and 4-fluorophenyl phosphonic dichloride to yield a pale yellow solid. The yellow solid was recrystallized from ethyl acetate to yield 1-(4-fluorophenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (5.9 g, 30% yield) as white needles having a melting point of 119°-120° C. and the following analysis:

Source