Réaction #2122518

Équation de réaction

Compound 20

N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide

p-toluenesulfonic acid methyl ester

hexane

→

Compound 21

Rendement 78.9%

6-(N,N-dihexylsulfamoyl)-2,3-dimethylbenzo[d]-thiazole-3-ium tosylate

Rendement 78.9%

Solvants

ethyl acetate

Conditions de réaction

Traitement

1. 1
   Températureto cool to room temperature
2. 2
   AutreA sticky dark brown solid separated which
3. 3
   Lavagewas washed with hexane
4. 4
   Autredried under vacuum

Mode opératoire

A mixture of Compound 20 (2.0 g, 5.0 mmol) and p-toluenesulfonic acid methyl ester (1.4 g, 7.5 mmol) was heated in a pressure tube at 130° C. for 2 hours. The mixture was allowed to cool to room temperature, and the resulting mass was dissolved in ethyl acetate (4 ml). The combined mixture was then added drop wise to hexane (40 ml). A sticky dark brown solid separated which was washed with hexane and dried under vacuum to yield 2.3 g (78%) of Compound 21 which was used without any further purification. The structure of this compound is given below:

Source