Réaction #2057

ord-d450d9a3b4314144865c4274817143d7

Équation de réaction

CCCCCCCCCCCCCCCCCCN(C)CCO
N-(2-hydroxyethyl)-N-methyloctadecylamine
CCCCCCCCCCCCCCCCCC(=O)O
octadecanoic acid
→
CCCCCCCCCCCCCCCCCCN(C)CCOC(=O)CCCCCCCCCCCCCCCCC
N-(2-octadecanoyloxyethyl)-N-methyloctadecylamine
Rendement 96.5%

Réactifs

CCCCCCCCCCCCCCCCCCN(C)CCO
N-(2-hydroxyethyl)-N-methyloctadecylamine
CCCCCCCCCCCCCCCCCC(=O)O
octadecanoic acid

Réactifs

Aucun

Conditions de réaction

Température
180°CELSIUS
Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreA four-neck flask provided with a stirrer
  2. 2
    Températuremaintained at this temperature for 12 hours
  3. 3
    workup.DISTILLATIONwhile distilling off the water
  4. 4
    Autrethus formed

Mode opératoire

A four-neck flask provided with a stirrer, a thermometer and a dehydrating tube was charged with 200 g of the N-(2-hydroxyethyl)-N-methyloctadecylamine and 174 g of octadecanoic acid. The mixture was heated to 180° C. and maintained at this temperature for 12 hours while distilling off the water thus formed. Thus 350 g of N-(2-octadecanoyloxyethyl)-N-methyloctadecylamine was obtained. Based on the NMR and IR spectra, it was confirmed that this product had the following structure. This compound will be referred to as the enhancer 25 hereinafter. ##STR31##

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05728649uspto-grants-1998_03