Réaction #2051997

Équation de réaction

Intermediate 2

3-amino-3-(1,3-benzodioxol-5-yl)-1-propanol

3-([1,1′-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxylic acid

Intermediate 8

3-([1,1′-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxylic acid

3-amino-3-(1,3-benzodioxol-5-yl)-1-propanol

→

title compound

N-[1-(1,3-benzodioxol-5-yl)-3-hydroxypropyl]-3-([1,1′-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxamide

Conditions de réaction

Mode opératoire

Following the general strategies and protocols outlined in Example 1, starting from 3-([1,1′-biphenyl]-4-ylsulfonyl)-1,3-thiazolidine-2-carboxylic acid (Intermediate 8) and 3-amino-3-(1,3-benzodioxol-5-yl)-1-propanol (Intermediate 2), the title compound was obtained in 92% purity by HPLC.

Source