Réaction #2028930

ord-5762e74bbce94cd5bdc2f97717ca399d

Équation de réaction

C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
D-Fucose
C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
D-fucose
→
C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO
D-fucitol

Réactifs

C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
D-Fucose
C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
D-fucose

Réactifs

[Ni]
Raney-nickel

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

D-Fucose (6-deoxy D-galactose) was reduced [a composition in total of 500 ml containing D-fucose at 1% and 20 ml of the Raney-nickel catalyst] to produce D-fucitol (6-deoxy D-galactitol). FIG. 57(a) shows HPLC analysis results of D-fucose before reduction and FIG. 57(b) shows HPLC analysis results of 6-deoxy L-galactitol after the reduction. The optical rotation of 6-deoxy L-galactitol was +1.7, and FIG. 58 shows 13C NMR spectrum of 6-deoxy L-galactitol.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08389248B2uspto-grants-2013_03