Réaction #2028881

Équation de réaction

alcohol

4-[3-hydroxymethyl-5-phenyl-1H-pyrazol-1-yl]benzene Sulfonamide

→

aldehyde

4-[3-formyl-5-phenyl-1H-pyrazol-1-yl]benzenesulfonamide

Solvants

ethyl acetate

Conditions de réaction

Traitement

1. 1
   FiltrationThe mixture was filtered through Celite
2. 2
   Concentrationthe solution was concentrated

Mode opératoire

To a solution of the alcohol prepared in Example 131, Step 3 (1.1 g, 3.3 mmol) in ethyl acetate (20 mL) was added MnO2 (5 g, 60 mmol) and the mixture stirred at room temperature overnight. The mixture was filtered through Celite and the solution was concentrated to provide the crude aldehyde.

Source