Réaction #2006469

ord-514aeeb6038d4973bd5ee82cdc2b3cb5

Équation de réaction

O=C([O-])C(=O)c1c[nH]c2ncccc12.[K+]
compound 3a
O=C([O-])C(=O)c1c[nH]c2ncccc12.[K+]
Potassium (7-azaindol-3-yl)-oxoacetate
CCOC(=O)C(=O)c1c[nH]c2c(OC)ncc(OC)c12
Ethyl (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate
→
COc1ncc(OC)c2c(C(=O)C(=O)[O-])c[nH]c12.[K+]
Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

Réactifs

O=C([O-])C(=O)c1c[nH]c2ncccc12.[K+]
compound 3a
O=C([O-])C(=O)c1c[nH]c2ncccc12.[K+]
Potassium (7-azaindol-3-yl)-oxoacetate
CCOC(=O)C(=O)c1c[nH]c2c(OC)ncc(OC)c12
Ethyl (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Compound 3ao (Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate) was prepared (as a yellow solid), by the same method used to prepare compound 3a except Ethyl (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate was employed as the starting material. MS m/z: (M+H)+ of the corresponding acid of compound 3ao (M-K+H)+ calcd for C11H11N2O5: 251.07; found 251.09. HPLC retention time: 0.69 minutes (column B).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08168615B2uspto-grants-2012_05