Réaction #1965653

Équation de réaction

Intermediate 1

6-bromo-N-phenylimidazo[1,2-a]pyridine-2-carboxamide

ethyl 6-cyanoimidazo[1,2-a]pyridine-2-carboxylate

→

N-phenyl-6-cyanoimidazo[1,2-a]pyridine-2-carboxamide

Conditions de réaction

Mode opératoire

By working in the same manner as for the preparation of Intermediate 1, replacing the ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate with ethyl 6-cyanoimidazo[1,2-a]pyridine-2-carboxylate (J. Med. Chem. (1998), 41(22), 4317), N-phenyl-6-cyanoimidazo[1,2-a]pyridine-2-carboxamide is obtained in the form of a yellow solid

Source