Réaction #1931287

Équation de réaction

4-methoxybenzamide

oxalyl chloride

→

title compound

4-Methoxybenzoyl isocyanate

Solvants

dichloromethane

Conditions de réaction

Traitement

1. 1
   TempératureThe mixture was heated
2. 2
   Températureto reflux for 20 h
3. 3
   AutreReaction completion
4. 4
   AutreThe solvent was removed in vacuo (40° C., 760 mmHg)

Mode opératoire

To 4-methoxybenzamide (2.6 mmol) in dichloromethane (10 mL) was added oxalyl chloride 98% (6.61 mmol) dropwise. The mixture was heated to reflux for 20 h. Reaction completion monitored by TLC. The solvent was removed in vacuo (40° C., 760 mmHg) to obtain title compound D11, which was immediately used without purification.

Source