Réaction #1929022

Équation de réaction

Benzoyl chloride

3-Nitrophenol

triethylamine

water

→

3-nitrophenyl benzoate

Rendement 90.3%

Solvants

dichloromethane

Conditions de réaction

Traitement

1. 1
   workup.STIRRINGthe resulting solution was shaken at room temperature until full conversion
2. 2
   SéchageThe organic phase was dried over magnesium sulfate
3. 3
   Filtrationfiltered
4. 4
   Autrethe solvent was removed under reduced pressure

Mode opératoire

3-Nitrophenol (1.716 g, 12.346 mmol) and triethylamine (1.6 mL, 12.346 mmol) were dissolved in 50 mL of dichloromethane. The solution was shaken 30 minutes at room temperature. Benzoyl chloride (1.43 mL, 12.346 mmol) was added drop by drop and the resulting solution was shaken at room temperature until full conversion as determined by thin-layer chromatography. Carbonated water (20 mL) was added three times. The organic phase was dried over magnesium sulfate, filtered and the solvent was removed under reduced pressure, thus affording 2.7080 g of a white solid corresponding to 3-nitrophenyl benzoate (11.144 mmol, yield=90%).

Source