Réaction #1909799

Équation de réaction

4-Phenylsulfanyl-[1,3]dioxolan-2-one

OXONE

water

→

4-benzenesulfonyl-[1,3]dioxolan-2-one

Solvants

methanol

methanol

Conditions de réaction

Traitement

1. 1
   AutreThe obtained reaction mixture
2. 2
   workup.STIRRINGwas agitated at room temperature for 12 hours
3. 3
   Autrewas removed
4. 4
   workup.DISTILLATIONdecompression distillation
5. 5
   Extractionthe resulting product was extracted
6. 6
   ExtractionThe extracted organic solvent layer was again extracted
7. 7
   Autrewas removed
8. 8
   Autreorganic solvent was removed
9. 9
   workup.DISTILLATIONdecompression distillation
10. 10
    AutreUsing silica gel chromatography, separation and purification

Mode opératoire

4-Phenylsulfanyl-[1,3]dioxolan-2-one) was dissolved in methanol, and OXONE® was added. The resulting mixture was agitated at room temperature for 5 minutes and water was added. The obtained reaction mixture was agitated at room temperature for 12 hours. From the agitated reaction mixture, methanol was removed using decompression distillation and the resulting product was extracted using methylene chloride. The extracted organic solvent layer was again extracted using water, moisture was removed using magnesium sulfate, and then organic solvent was removed using decompression distillation. Using silica gel chromatography, separation and purification were performed to obtain a pure target product, 4-benzenesulfonyl-[1,3]dioxolan-2-one.

Source