Réaction #1906468

Équation de réaction

decahydroisoquinoline mesylate

→

2-mercaptobenzonitrile

Solvants

acetone

potassium carbonate

Conditions de réaction

Mode opératoire

Following the procedures for Example 22, Step C, decahydroisoquinoline mesylate from preparation 3 (102 mg, 0.28 mmol) in acetone (0.5 mL), potassium carbonate solid (38 mg, 0.28 mmol, twice) and 2-mercaptobenzonitrile (38 mg, 0.286 mmol, twice) gave, after flash chromatography (hexanes-ethyl acetate 2:1), the desired product as an oil (64 mg) in 57% yield.

Source