Réaction #1890159

Équation de réaction

10-phenyldecanoic acid

(R)-3-amino-4-dimethylamino-butyric acid benzyl ester dihydrochloride

→

(R)-4-dimethylamino-3-(10-phenyl-decanoylamino)-butyric acid benzyl ester

Conditions de réaction

Mode opératoire

The title compound, m/e=377.3 ([M+H]+), was produced in analogy with intermediate 1, steps 3 and 4. Thus, commercially available 10-phenyldecanoic acid was coupled in step 3 with (R)-3-amino-4-dimethylamino-butyric acid benzyl ester dihydrochloride to produce (R)-4-dimethylamino-3-(10-phenyl-decanoylamino)-butyric acid benzyl ester, which was hydrogenated in step 4.

Source