Réaction #1859546

ord-5ef46302fbfb4ec2a88a64e2925b00a7

Équation de réaction

Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(C)(C)c1nnc(C)n1-2
Compound 214
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(C)(C)c1nnc(C)n1-2
4-(4-chlorophenyl)-2,3,6,6,9-pentamethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
CCOC(=O)C1(N)CCC1.Cl
ethyl 1-aminocyclobutanecarboxylate hydrochloride
→
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC1(CCC1)C(=O)N2
5′-(4-chlorophenyl)-6′,7′-dimethylspiro[cyclobutane-1,3′-thieno[2,3-e][1,4]diazepin]-2′(1′H)-one

Réactifs

Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(C)(C)c1nnc(C)n1-2
Compound 214
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(C)(C)c1nnc(C)n1-2
4-(4-chlorophenyl)-2,3,6,6,9-pentamethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
CCOC(=O)C1(N)CCC1.Cl
ethyl 1-aminocyclobutanecarboxylate hydrochloride

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

A procedure analogous to that set forth in the synthesis of Compound 214 was followed, with the exception that ethyl 1-aminocyclobutanecarboxylate hydrochloride was used as starting material. LRMS (M+H)+: 345 m/z.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US09249161B2uspto-grants-2016_02