Réaction #1840872

Équation de réaction

benzyltrimethylammonium 1,1,3,3,3-pentafluoro-2-hydroxypropane-1-sulfonate

bis(3,5-dimethylphenyl)-(4-fluorophenyl)-sulfonium bromide

methylene chloride

→

target compound

Rendement 92.0%

bis(3,5-dimethylphenyl)-(4-fluorophenyl)-sulfonium 1,1,3,3,3-pentafluoro-2-hydroxypropane-1-sulfonate

Rendement 92.0%

Solvants

water

Conditions de réaction

Traitement

1. 1
   Autresynthesized
2. 2
   AutreThe organic layer was separated
3. 3
   Lavagewashed with water
4. 4
   Concentrationconcentrated in vacuum
5. 5
   workup.ADDITIONTo the residue, diisopropyl ether was added for recrystallization
6. 6
   FiltrationThe resulting crystals were collected by filtration
7. 7
   Autredried in vacuum

Mode opératoire

A mixture of 21 g of benzyltrimethylammonium 1,1,3,3,3-pentafluoro-2-hydroxypropane-1-sulfonate synthesized according to the method of JP-A 2012-107151, the solution containing bis(3,5-dimethylphenyl)-(4-fluorophenyl)-sulfonium bromide obtained in Synthesis Example 1-47, 30 g of methylene chloride, and 50 g of deionized water was stirred for 30 minutes. The organic layer was separated, washed with water, and concentrated in vacuum. To the residue, diisopropyl ether was added for recrystallization. The resulting crystals were collected by filtration and dried in vacuum, obtaining 26 g of the target compound, bis(3,5-dimethylphenyl)-(4-fluorophenyl)sulfonium 1,1,3,3,3-pentafluoro-2-hydroxypropane-1-sulfonate as white crystals. Yield 92%.

Source