Réaction #1833264

ord-85986e9e902f4e05b97c138d51084269

Équation de réaction

C[O-].[Na+]
NaOMe
Cl.N[C@@H]1C[C@H]1c1ccccc1
(trans)-2-phenylcyclopropanamine hydrochloride
→
N[C@@H]1C[C@H]1c1ccccc1
(Trans)-2-phenylcyclopropanamine

Réactifs

C[O-].[Na+]
NaOMe
Cl.N[C@@H]1C[C@H]1c1ccccc1
(trans)-2-phenylcyclopropanamine hydrochloride

Réactifs

Aucun

Solvants

CO
MeOH

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe solvent was removed to dryness

Mode opératoire

NaOMe (0.80 g, 11.8 mmol) was added over a solution of (trans)-2-phenylcyclopropanamine hydrochloride (2.00 g, 11.8 mmol) in MeOH (40 mL) and stirred 1 hour. The solvent was removed to dryness.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US09149447B2uspto-grants-2015_10