Réaction #1827242

Équation de réaction

urocanic acid

methanol

→

crude product 2

methyl 3-(4-imidazolyl)-2-propenoate

Conditions de réaction

Traitement

1. 1
   Autrewas bubbled HCl gas until the solution
2. 2
   Concentrationconcentrated in vacuo to dryness

Mode opératoire

Through a suspension of urocanic acid (5.0 g) in methanol at 0° C. was bubbled HCl gas until the solution was saturated. The reaction was stirred for one hour, then concentrated in vacuo to dryness to provide the crude product 2 which was used in the next step without further purification.

Source