Réaction #1797526

ord-8ecfd13d154148eea2813219dd230976

Équation de réaction

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
NC1CCCCC1
cyclohexylamine
→
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1NC1CCCCC1
5-Cyclohexylamino-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

Réactifs

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
NC1CCCCC1
cyclohexylamine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

5-Cyclohexylamino-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and cyclohexylamine. Mass spectrum (ES) MH+=419.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07790711B2uspto-grants-2010_09