Réaction #1752

ord-fb382a38ecde4b3498d73cf8d48e3315

Équation de réaction

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)CC=Cc1ccccc1
4-phenyl-3-butenoic acid chloride triethylamine
→
CN(C)Cc1ccc([C@H]2CC[C@H](OC(=O)CC=Cc3ccccc3)CC2)cc1
trans-O-(4-phenyl-3-butenoyl)-4-(4-dimethylaminomethylphenyl)-cyclohexanol

Réactifs

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)CC=Cc1ccccc1
4-phenyl-3-butenoic acid chloride triethylamine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

from trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol and 4-phenyl-3-butenoic acid chloride/triethylamine. White crystals.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05726205uspto-grants-1998_03