Réaction #172508

Équation de réaction

4-(dibutylamino)-2-methoxybenzaldehyde

1,3-bis(dicyanomethylidene)indan

water

→

black crystal

Rendement 86.5%

2-[2-(4-dibutylamino-2-methoxybenzylidene)-3-dicyanomethyleneindan-1-ylidene]malonnitrile

Rendement 86.5%

Solvants

acetic acid

Conditions de réaction

Traitement

1. 1
   Autrethe precipitate was separated by filtration
2. 2
   Lavagewashed with water
3. 3
   Autredried
4. 4
   AutreThe crystal was purified by silica gel column chromatography
5. 5
   Lavagewashed with methanol

Mode opératoire

In 10 ml of anhydrous acetic acid were dissolved 0.8 g (3.04 mmol) of 4-(dibutylamino)-2-methoxybenzaldehyde and 0.73 g (3.01 mmol) of 1,3-bis(dicyanomethylidene)indan. The mixture was stirred with heating at 80° C. for 2 hours. The reaction mixture was poured into 200 ml of water and the precipitate was separated by filtration, washed with water, and dried. The crystal was purified by silica gel column chromatography and washed with methanol to give 1.27 g of a black crystal having a mp of 195-198° C. (yield: 86.4%).

Source