Réaction #168212

Équation de réaction

3,5-dichloroisonicotinonitrile

4-benzoylphenylboronic acid

→

3-(4-benzoylphenyl)-5-chloroisonicotinonitrile

Rendement 80.0%

Conditions de réaction

Mode opératoire

Following conditions described in Step 1 of Example 50, 3,5-dichloroisonicotinonitrile was reacted with 4-benzoylphenylboronic acid to give 3-(4-benzoylphenyl)-5-chloroisonicotinonitrile (˜80% pure). MS (ES+) m/z: 351 (M+H); LC retention time: 3.980 min (analytical HPLC Method A). Step 2:

Source