Réaction #165996

Équation de réaction

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

intermediate 1

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

2-(R)-hydroxypropylamine

→

3-[(2-fluoro-4-iodophenyl)amino]-N-[(2R)-2-hydroxypropyl]isonicotinamide

Conditions de réaction

Mode opératoire

3-[(2-fluoro-4-iodophenyl)amino]-N-[(2R)-2-hydroxypropyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 2 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 3 mmol of 2-(R)-hydroxypropylamine LC/MS [8.33 min; 416 (M+1)]

Source