Réaction #165989

Équation de réaction

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

intermediate 1

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

2-(R)-hydroxypropylamine

→

3-[(2-fluoro-4-iodophenyl)amino]-N-[(2S)-2-hydroxypropyl]isonicotinamide

Conditions de réaction

Traitement

1. 1
   AutreLC/MS [8.40 min; 416 (M+1)]

Mode opératoire

3-[(2-fluoro-4-iodophenyl)amino]-N-[(2S)-2-hydroxypropyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.3 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.4 mmol of 2-(R)-hydroxypropylamine. LC/MS [8.40 min; 416 (M+1)]

Source