Réaction #165546

Équation de réaction

5-amino-2-methylphenol

4-chloro-N-methyl-2-pyridinecarboxamide

→

3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline

Conditions de réaction

Traitement

1. 1
   Autrehad been synthesized

Mode opératoire

Entry 50: According to Method A2, Step 4, 5-amino-2-methylphenol was reacted with 4-chloro-N-methyl-2-pyridinecarboxamide, which had been synthesized according to Method A2, Step 3b, to give 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline to afford the urea.

Source