Réaction #1619

Équation de réaction

(R)-3-(3,4-dimethoxyphenyl)-2-propylamine

hydrogen bromide

→

title compound

(R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

Conditions de réaction

Traitement

1. 1
   TempératureAfter cooling
2. 2
   Autrethe solvent was evaporated
3. 3
   Autrethe residue was dried

Mode opératoire

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

Source