Réaction #1608

Équation de réaction

6-(4-chlorophenyl)-pyridazinone

phosphorus pentasulfide

→

6-(4-chlorophenyl)-pyridazinthione

Rendement 187.1%

Solvants

pyridine

Conditions de réaction

Traitement

1. 1
   Températurewas refluxed for 1 hour
2. 2
   Autreevaporated to dryness
3. 3
   Extractionextracted with 200 ml of ether
4. 4
   ExtractionThe ether extract
5. 5
   Lavagewas washed with water (3×100 ml), brine (100 ml)
6. 6
   Séchagedried over magnesium sulfate
7. 7
   Autreevaporated

Mode opératoire

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

Source