Réaction #160622

Équation de réaction

1-allyl-cyclopropanesulfonyl chloride

5,6-difluoro-N1-(2-fluoro-4-iodophenyl)-3-(2-methoxyethoxy)benzene-1,2-diamine

→

title product

Rendement 78.0%

1-Allyl-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-(2-methoxyethoxy)phenyl)cyclopropane-1-sulfonamide

Rendement 78.0%

Conditions de réaction

Mode opératoire

According to the general procedure B, 1-allyl-cyclopropanesulfonyl chloride (450 rug, 2.5 mmol) was reacted with 5,6-difluoro-N1-(2-fluoro-4-iodophenyl)-3-(2-methoxyethoxy)benzene-1,2-diamine (219 mg, 2.5 mmol) to obtain the title product (230 mg, 78%); m/z=581 [M−1].

Source