Réaction #159011

Équation de réaction

6-Bromonaphthalene-2-carboxylic acid

thionyl chloride

→

6-bromonaphthalene-2-carbonyl chloride

Conditions de réaction

Traitement

1. 1
   Autreevaporated under vacuum
2. 2
   workup.DISSOLUTIONSolid was dissolved in dichloromethane (50 mL)
3. 3
   Autreevaporated under vacuum

Mode opératoire

6-Bromonaphthalene-2-carboxylic acid (25.1 g) was suspended in thionyl chloride (200 mL), stirred at 60° C. for 16 hours and evaporated under vacuum. Solid was dissolved in dichloromethane (50 mL) and evaporated under vacuum, giving 6-bromonaphthalene-2-carbonyl chloride (27.0 g, crude) as a white solid.

Source