Réaction #1563888

ord-46c5fcb07c94481a8e8f0d3a8d9e85a9

Équation de réaction

COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1
2-amino-N-(2-methoxyphenyl)-6-(4-nitrophenyl-thio)benzamide
O=S(=O)(O)O
H2SO4
→
COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1.O=S(=O)(O)O
2-amino-N-(2-methoxyphenyl)-6-(4-nitrophenyl-thio)benzamide sulfate
Rendement 72.0%

Réactifs

COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1
2-amino-N-(2-methoxyphenyl)-6-(4-nitrophenyl-thio)benzamide
O=S(=O)(O)O
H2SO4

Réactifs

Aucun

Solvants

CCOC(C)=O
EA

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    FiltrationThe reaction mixture was filtered
  2. 2
    Autreto get White solid

Mode opératoire

2-amino-N-(2-methoxyphenyl)-6-(4-nitrophenyl-thio)benzamide dissolved in EA, stirred at room temperature, while dropped H2SO4 into mixture till occurred to white solid. The reaction mixture was filtered to get White solid; 72% yield;

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US09402819B2uspto-grants-2016_08