Réaction #1559824

Équation de réaction

2-chloroquinolin-6-ol

Intermediate 2

2-chloroquinolin-6-ol

4-borono-2-fluorobenzoic acid

→

2-fluoro-4-(6-hydroxyquinolin-2-yl)benzoic acid

Conditions de réaction

Mode opératoire

Followed Scheme 3: Starting Materials: 2-chloroquinolin-6-ol (Intermediate 2) and 4-borono-2-fluorobenzoic acid. 1H NMR (CD3OD, 400 MHz): δ 8.54 (d, J=8.4 Hz, 1H), 8.20-8.06 (m, 3H), 8.06-7.96 (m, 2H), 7.55 (dd, J=9.2, 2.4 Hz, 1H), 7.32 (d, J=2.8 Hz, 1H). MS (ESI): m/z 283.6 [M+1]+.

Source