Réaction #155407

Équation de réaction

N-Boc-3-azetidinone

ethanolamine

→

N—(N-Boc-azetidin-3-yl)-2-amino-ethanol

Rendement 62.3%

Conditions de réaction

Mode opératoire

N-Boc-3-azetidinone (1.0 g, 5.84 mmol) was treated with ethanolamine following Procedure 1-Method A to yield N—(N-Boc-azetidin-3-yl)-2-amino-ethanol (0.75 g, 3.46 mmol, 62.3% yield): MS m/e [M+H]+ calcd 217.1. found 217.2.

Source