Réaction #155368

Équation de réaction

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]-propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenyl-amino)-propionic acid methyl ester

Solvants

THF

Conditions de réaction

Traitement

1. 1
   AutreAfter completion of the reaction the mixture
2. 2
   Autrewas evaporated to dryness
3. 3
   Autrethe crude product was used without further purification

Mode opératoire

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

Source