Réaction #1552054

Équation de réaction

methyl-4-bromobenzoate

hydrazine monohydrate

→

white solid

Rendement 67.0%

4-bromobenzohydrazide

Rendement 67.0%

Solvants

ethanol

Conditions de réaction

Traitement

1. 1
   Températurethe mixture was heated
2. 2
   workup.STIRRINGstirred at 78° C. for 5 hours
3. 3
   AutreA solid obtained
4. 4
   Lavagewashed with water
5. 5
   Filtrationcollected by suction filtration

Mode opératoire

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added therein, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added therein, and the mixture was heated and stirred at 78° C. for 5 hours. A solid obtained washed with water and collected by suction filtration; thus, 2.0 g of a white solid of objective 4-bromobenzohydrazide was obtained (yield: 67%).

Source