Réaction #1552050

Équation de réaction

1,8-octanediamine

triethylamine

furoyl chloride

→

N,N′-(octane-1,8-diyl)bis(furan-2-carboxamide)

Conditions de réaction

Traitement

1. 1
   AutreThe resulting compound was purified by column chromatography (98:2 DCM:EtOAc)
2. 2
   Autrethe product obtained as a white solid (21.5 g/92%)

Mode opératoire

The general procedure was carried out using 1,8-octanediamine (10.0 g, 69.3 mmol), triethylamine (14.2 g, 141 mmol), DMAP (0.17 g, 1.35 mmol) and furoyl chloride (19.0 g, 146 mmol). The resulting compound was purified by column chromatography (98:2 DCM:EtOAc), and the product obtained as a white solid (21.5 g/92%).

Source