Réaction #1545405

ord-633454f290d44ddfb96af719dbb17d03

Équation de réaction

Cc1ncsc1C=O
4-methyl-5-thiazolecarbaldehyde
CN(C)c1cccc(Br)c1
3-bromo-N,N-dimethylaniline
→
Cc1ncsc1C(O)c1cccc(N(C)C)c1
title compound
Cc1ncsc1C(O)c1cccc(N(C)C)c1
1-(3-Dimethylaminophenyl)-1-(4-methyl-5-thiazolyl)-methanol

Réactifs

Cc1ncsc1C=O
4-methyl-5-thiazolecarbaldehyde
CN(C)c1cccc(Br)c1
3-bromo-N,N-dimethylaniline

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The title compound was prepared from 4-methyl-5-thiazolecarbaldehyde and 3-bromo-N,N-dimethylaniline using the method of Example 32. M.p. 135°-138° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05849921uspto-grants-1998_12