Réaction #1520301

Équation de réaction

sodium

3,5-dimethyl-1,1′-biadamantane

Compound A4

3,5-dimethyl-1,1′-biadamantane

1-bromoadamantane

1-bromo-3,5-dimethyladamantane

Compound A4

3,5-dimethyl-1,1′-biadamantane

bromine

Compound A5

3′-bromo-3,5-dimethyl-1,1′-biadamantane

3′-bromo-3,5-dimethyl-1,1′-biadamantane

Compound ( A5 )

3′-bromo-3,5-dimethyl-1,1′-biadamantane

1-bromo-3,5-dimethyladamantane

→

Compound A6

1,3-bis-(3,5-dimethyl-1-adamantyl)adamantane

Solvants

m-xylene

Conditions de réaction

Traitement

1. 1
   Autreis prepared

Mode opératoire

In the following manner, 1,3-bis-(3-ethynyl-5,7-dimethyl-1-adamantyl)adamantane (Exemplified compound (D-32) is obtained. Described specifically, a coupling reaction between 1-bromoadamantane and 1-bromo-3,5-dimethyladamantane is caused in m-xylene by the addition of metal sodium, whereby 3,5-dimethyl-1,1′-biadamantane (Compound A4) is prepared. Compound A4 is then brominated with bromine into 3′-bromo-3,5-dimethyl-1,1′-biadamantane (Compound A5). Compound (A5) is reacted with 1-bromo-3,5-dimethyladamantane to obtain 1,3-bis-(3,5-dimethyl-1-adamantyl)adamantane (Compound A6). The resulting compound is then treated in a similar manner to that shown in <Synthesis of Exemplified compound (D-2)>, whereby Exemplified compound (D-32) is obtained.

Source