Réaction #1519131

ord-05822195b40e4fef8b000895bfc577aa

Équation de réaction

c1cncc(C2CCNC2)c1
3-pyrrolidin-3-yl-pyridine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
→
CCCC[C@@H](C(=O)N1CCC(c2cccnc2)C1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCC(c2cccnc2)C1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[3 (R/S)-pyridin-3-yl-pyrrolidine-1-carbonyl)-heptanoic acid

Réactifs

c1cncc(C2CCNC2)c1
3-pyrrolidin-3-yl-pyridine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 3-pyrrolidin-3-yl-pyridine A-5 according to General Procedure B.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07612059B2uspto-grants-2009_11