Réaction #1470434

ord-76b363e594564a2d8c67cb9104848a40

Équation de réaction

CC1(C)CC(O)CC(C)(C)N1O
1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine
O=S(=O)(O)O
sulfuric acid
→
CC1(C)CC(O)CC(C)(C)[NH+]1O.CC1(C)CC(O)CC(C)(C)[NH+]1O.O=S(=O)([O-])[O-]
product
CC1(C)CC(O)CC(C)(C)[NH+]1O.CC1(C)CC(O)CC(C)(C)[NH+]1O.O=S(=O)([O-])[O-]
Bis-(1-hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidinium) Sulfate

Réactifs

—
Pt
CC1(C)CC(O)CC(C)(C)N1O
1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine
O=S(=O)(O)O
sulfuric acid
—
glass

Réactifs

Aucun

Solvants

O
water

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreCatalyst is removed by filtration through a pad of Celite
  2. 2
    AutreRemoval of water

Mode opératoire

To a glass 0.5L reaction bottle are added 10.0 g (58 mmol) of 1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine, 2.85g (29 mmol) sulfuric acid, 200 mg 5% Pt on C and 100 mL water. Catalytic hydrogenation is carried out at 50 psi for 30 minutes at room temperature. Catalyst is removed by filtration through a pad of Celite. Removal of water yields the product as an pale yellow solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06254724B1uspto-grants-2001_07