Réaction #1470425

Équation de réaction

1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

diethanolamine

→

title compound

Rendement 29.9%

1-Oxyl-2,2,6,6-tetramethyl-4-{2-hydroxy-3-[di(2-hydroxyethyl)amino]propoxy}piperidine

Rendement 29.9%

Solvants

water

Conditions de réaction

Traitement

1. 1
   ExtractionThe solution is then extracted with methylene chloride
2. 2
   ExtractionThe methylene chloride extract
3. 3
   Séchageis dried over anhydrous magnesium sulfate
4. 4
   Filtrationfilter
5. 5
   Concentrationconcentrated
6. 6
   AutreThe crude reaction product
7. 7
   Autreis purified by column chromatography

Mode opératoire

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

Source