Réaction #1470424

Équation de réaction

1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine

epichlorohydrin

→

title compound

1-Oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

Solvants

sodium hydroxide

toluene

Conditions de réaction

Traitement

1. 1
   Autreis reacted together
2. 2
   SéchageThe organic phase is dried over anhydrous magnesium sulfate
3. 3
   Concentrationconcentrated

Mode opératoire

A vigorously stirred two phase solution of 1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine, epichlorohydrin, tetrabutylammonium bromide in 50% aqueous sodium hydroxide and toluene is reacted together. The organic phase is dried over anhydrous magnesium sulfate and concentrated to yield the title compound as a low melting red solid after column chromatography.

Source