Réaction #1442484

Équation de réaction

Boric acid

glycerol

salicylamide

→

salicylamide glycerol borate

Rendement 88.2%

Solvants

toluene

Conditions de réaction

Traitement

1. 1
   AutreSalicylamide/glycerol borate was prepared
2. 2
   Autrethe byproduct water (˜9 grams) was continuously removed from the reaction by azeotropic distillation
3. 3
   AutreThe final solution was evaporated
4. 4
   Autreto remove toluene under vacuum

Mode opératoire

Salicylamide/glycerol borate was prepared as follows. Boric acid (10.3 grams), glycerol (15.3 grams), and salicylamide (22.9 grams) were added to a 250 milliliter flask. One hundred fifty milliliters of toluene was then added. The reaction was allowed to proceed overnight at 110° C., and the byproduct water (˜9 grams) was continuously removed from the reaction by azeotropic distillation. The final solution was evaporated to remove toluene under vacuum, and a yellowish resinous product (˜40 grams) of salicylamide/glycerol borate was obtained.

Source