Réaction #1340989

ord-51a27112b4784313a05662809ce89109

Équation de réaction

Cc1cc(Br)c(C)nc1O
5-bromo-3,6-dimethylpyridin-2-ol
Cc1ccc(S(=O)(=O)OCCC(C)(C)O)cc1
3-hydroxy-3-methylbutyl 4-methylbenzenesulfonate
Cc1cc(Br)c(C)nc1OCCC(C)(C)O
compound
Rendement 75.8%
Cc1cc(Br)c(C)nc1OCCC(C)(C)O
4-(5-bromo-3,6-dimethylpyridin-2-yl)oxy-2-methylbutan-2-ol
Rendement 75.8%

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

According to the method of (Example 36) <Step 1>, from 5-bromo-3,6-dimethylpyridin-2-ol (0.74 g) and 3-hydroxy-3-methylbutyl 4-methylbenzenesulfonate (1.0 g), the subject compound (0.80 g) was obtained as a white solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08455500B2uspto-grants-2013_06