Réaction #1340577

Équation de réaction

octadecyl succinic anhydride

ethanolamine

→

N-(2-hydroxyethyl)octadecyl succinimide

Rendement 54.0%

Conditions de réaction

Traitement

1. 1
   AutreA 50 mL reaction flask
2. 2
   Autrethe resulting mixture was reacted at 160° C. for 4 hours under continuous nitrogen purging and with vigorous stirring
3. 3
   AutreThe reaction product was purified by silica gel column chromatography (mobile phase: ethyl acetate/hexane)

Mode opératoire

A 50 mL reaction flask was charged with 17.6 g of octadecyl succinic anhydride (manufactured by Tokyo Chemical Industry Co., Ltd.) and 3.1 g of ethanolamine (manufactured by Tokyo Chemical Industry Co., Ltd.), and the resulting mixture was reacted at 160° C. for 4 hours under continuous nitrogen purging and with vigorous stirring. The reaction product was purified by silica gel column chromatography (mobile phase: ethyl acetate/hexane), yielding 10.6 g of N-(2-hydroxyethyl)octadecyl succinimide (yield: 54%).

Source