Réaction #1256189

Équation de réaction

SOCl2

D-phenylglycine

EtOH

→

D-Phg-OEt hydrochloride

Conditions de réaction

Traitement

1. 1
   TempératureThe cooling of the reaction
2. 2
   ConcentrationAfter concentrating the reaction mixture under reduced pressure, Et2O
3. 3
   workup.ADDITIONwas added to the crude crystals
4. 4
   Filtrationfiltered

Mode opératoire

SOCl2 (4.3 ml) was added to an EtOH suspension (150 ml) of D-phenylglycine (8.00 g) at −50° C. The cooling of the reaction was stopped and then stirred for 71 hours at room temperature. After concentrating the reaction mixture under reduced pressure, Et2O was added to the crude crystals and then filtered to obtain the D-Phg-OEt hydrochloride.

Source