Réaction #1251077

ord-1c52e624bdf54dd2b3297b662a3500b4

Équation de réaction

Cc1cc(OCC2CO2)c(N)c([N+](=O)[O-])c1
2-(2,3-epoxypropoxy)-4-methyl-6-nitroaniline
CC(C)N
2-propylamine
→
Cc1cc(OCC(O)CNC(C)C)c(N)c([N+](=O)[O-])c1
2-[2-hydroxy-3-(2-propylamino)-propoxy]-4-methyl-6-nitroaniline

Réactifs

—
diamine
Cc1cc(OCC2CO2)c(N)c([N+](=O)[O-])c1
2-(2,3-epoxypropoxy)-4-methyl-6-nitroaniline
CC(C)N
2-propylamine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autreis obtained

Mode opératoire

The diamine used as intermediate is obtained by reacting the 2-(2,3-epoxypropoxy)-4-methyl-6-nitroaniline described in Example 1 with 2-propylamine to give 2-[2-hydroxy-3-(2-propylamino)-propoxy]-4-methyl-6-nitroaniline, which is then subjected to catalytic hydrogenation.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04367235uspto-grants-1983_01