Réaction #1241703

Équation de réaction

2-ethoxyethyl 5-chlorobenzoxazol-2-carboxylate

ethoxyethylamine

→

product

Rendement 90.3%

N-(Ethoxyethyl)-5-chlorobenzoxazole-2-carboxamide

Rendement 90.3%

Solvants

THF

Conditions de réaction

Traitement

1. 1
   FiltrationThe precipitated product was filtered
2. 2
   Lavagewashed well with hexane

Mode opératoire

A mixture of 2-ethoxyethyl 5-chlorobenzoxazol-2-carboxylate (10 g) and 3.5 g of ethoxyethylamine in 10 ml of THF was stirred at room temperature for 2 hours. The precipitated product was filtered and washed well with hexane to give 9 g of product; mp 110°-111° C.

Source