Réaction #12079

Équation de réaction

sodium chlorodifluoroacetate

chlorotriethoxysilane

→

chlorodifluoroacetic acid, triethoxysilyl ester

Solvants

Et2O

Et2O

Conditions de réaction

Traitement

1. 1
   Températureto warm up to room temperature
2. 2
   AutreNaCl is removed by filtration and solution
3. 3
   Autreevaporated to dryness

Mode opératoire

15.246 g (0.10 mol) sodium chlorodifluoroacetate, is dissolved to 100 mL Et2O and cooled to −70° C. 19.7 mL (0.10 mol, 19.872 g) chlorotriethoxysilane in Et2O (50 mL) was added dropwise to reaction solution. The solution was stirred for over night allowing it to warm up to room temperature. NaCl is removed by filtration and solution evaporated to dryness to result clear colourless liquid, chlorodifluoroacetic acid, triethoxysilyl ester.

Source