Réaction #1178397

Équation de réaction

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

Rendement 91.0%

Solvants

THF

Conditions de réaction

Traitement

1. 1
   Températurewas refluxed for 20 h
2. 2
   Filtrationfiltered
3. 3
   AutreThe filtrates were evaporated
4. 4
   Autrethe crude product was purified by a silica gel column

Mode opératoire

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

Source