Réaction #1178395

Équation de réaction

4,4′-dihydroxybenzophenone

→

1,1,2,2-tetrakis(4-hydroxyphenyl)ethylene

Rendement 83.0%

Solvants

THF

Conditions de réaction

Traitement

1. 1
   Températurewas refluxed for 20 h
2. 2
   Filtrationfiltered
3. 3
   AutreThe filtrates were evaporated
4. 4
   Autrethe crude product was purified by a silica gel column
5. 5
   AutreDHTPE was obtained as slight yellow powder of 83% yield

Mode opératoire

A suspension of 4,4′-dihydroxybenzophenone (3.0 g, 14.0 mmol), 1 equiv of TiCl4 (1.54 ml, 14.0 mmol), and 2 equiv of Zn dust (1.83 g, 28.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using ethyl acetate (EA) as eluent. DHTPE was obtained as slight yellow powder of 83% yield.

Source